Recombinant Mouse CD27/TNFRSF7 Protein (His & Fc Tag)(Active)

    • Recombinant Mouse CD27 / TNFRSF7 Protein (His & Fc tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Mouse CD27 / TNFRSF7 Protein (His & Fc tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Mouse CD27 / TNFRSF7 Protein (His & Fc tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSM040860

      Synonyms:CD27 antigen; CD27L receptor; T-cell activation antigen CD27; Tumor necrosis factor receptor superfamily member 7;S152;Tnfrsf7;Tp55

      Size:
      • 50 μg
      • 100 μg
      Qty:
      - +
      Price: $454

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms CD27 antigen; CD27L receptor; T-cell activation antigen CD27; Tumor necrosis factor receptor superfamily member 7;S152;Tnfrsf7;Tp55
      Species Mouse
      Expression_host HEK293 Cells
      Sequence Met 1-Arg 182
      Accession NP_001028298.1
      Application Functional ELISA
      Mol_Mass 46.2 kDa
      AP_Mol_Mass 60-65 kDa
      Tag C-His-Fc
      Bio_Activity Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse CD27 at 2 µg/ml (100 μl/well) can bind biotinylated human CD70 with a linear range of 0.39-12.5 ng/ml.

      Properties

      Purity > 94 % as determined by SDS-PAGE
      Endotoxin < 1.0 EU per µg of the protein as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile PBS, pH 7.4
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has important role in generation of T cell immunity, and is an apparently robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.

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      MSDS for ELISA ISO 9001

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