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Recombinant Mouse G-CSF/CSF3 Protein (His Tag)

Uniprot : P09920
  • Cat.No.:PKSM041034

  • Expression host: HEK293 Cells

To Purchase PKSM041034

Size:
  • 10μg
  • 50μg
Price: $178
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Description

Synonyms Granulocyte colony-stimulating factor;Csf3;G-CSF
Species Mouse
Expression_host HEK293 Cells
Sequence Val31-Ala208
Accession P09920
Mol_Mass 19.8 kDa
AP_Mol_Mass 25 kDa
Tag C-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 10mM Sodium Citrate, 0.1% Tween 20, pH 3.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent.

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