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Recombinant Mouse Interleukin-11/IL-11 Protein (Fc Tag)

Uniprot : P47873

Cat.No.:PKSM041323
Expression host: HEK293 Cells

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Description

Synonyms	Interleukin-11;Il11;IL-11
Species	Mouse
Expression_host	HEK293 Cells
Sequence	Pro22-Leu199
Accession	P47873
Mol_Mass	46.3 kDa
AP_Mol_Mass	50-60 kDa
Tag	C-Fc

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 0.004% Tween80, 5% Mannitol, pH 4.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific bu
Reconstitution	Please refer to the printed manual for detailed information.

Background

Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.

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