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Recombinant Human Apolipoprotein C-II/APOC2 Protein (His Tag)

Uniprot : P02655
  • Cat.No.:PKSH032084

  • Expression host: E.coli

To Purchase PKSH032084

Size:
  • 10μg
  • 50μg
Price: $223
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Description

Synonyms Apolipoprotein C-II;Apolipoprotein C2;APC2 and APOC2
Species Human
Expression_host E.coli
Sequence Thr23-Glu101
Accession AAP35354.1
Mol_Mass 10.0 kDa
AP_Mol_Mass 14 kDa
Tag C-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH 7.4.
Reconstitution Not Applicable

Background

APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.

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