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Recombinant Human Arginase-1/ARG1 Protein (E.coli, His Tag)

Uniprot : P05089

Cat.No.:PKSH032091
Expression host: E.coli

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Description

Synonyms	Arginase-1;Liver-type arginase;Type I arginase;ARG1
Species	Human
Expression_host	E.coli
Sequence	Met 1-lys322
Accession	P05089
Mol_Mass	35.8 kDa
AP_Mol_Mass	40 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, 1mM DTT, pH 7.4.
Reconstitution	Not Applicable

Background

ARG1 is a member of the ureohydrolase family of enzymes. ARG1 can catalyze the hydrolysis of arginine to ornithine and urea. In the urea cycle, ARG1 catalyzes the fifth and final step, a series of biochemical reactions in mammals during which the body disposes of harmful ammonia. ARG1 is a cytosolic enzyme and expressed widely in the liver as part of the urea cycle. Inherited deficiency of this ARG1 causes argininemia, which is an autosomal recessive disorder characterized by hyperammonemia.

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