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Recombinant Human Carboxypeptidase B1/CPB1 Protein (His Tag)

Uniprot : P15086

Cat.No.:PKSH032171
Expression host: HEK293 Cells

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Description

Synonyms	Carboxypeptidase B;Pancreas-Specific Protein;PASP;CPB1;CPB;PCPB
Species	Human
Expression_host	HEK293 Cells
Sequence	His16-Tyr417
Accession	P15086
Mol_Mass	46.9 kDa
AP_Mol_Mass	47 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.
Reconstitution	Not Applicable

Background

Carboxypeptidase B1 is an exopeptidase which specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. Expressed mainly in pancreas, CPB1 is a useful serum marker for acute pancreatitis and pancreatic graft rejection.Human CPB1 consists of a signal peptide, a pro region, and a mature chain. The purified rhCPB1 corresponds to the pro form, which can be activated by trypsin, the only pancreatic protease capable of generating active enzyme from the zymogen in vitro.

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