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Recombinant Human CGA&CGB3 Heterodimer Protein (His & Flag Tag)

Uniprot : P01215&P0DN86

Cat.No.:PKSH033665
Expression host: HEK293 Cells

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Description

Synonyms	Beta-Nerve Growth Factor;Beta-NGF;NGF;NGFB
Species	Human
Expression_host	HEK293 Cells
Sequence	Ala25-Ser116&Ser21-Gln165
Accession	P01215&P0DN86
Mol_Mass	11.6&16.6 kDa
AP_Mol_Mass	22&30-35 kDa
Tag	C-Flag & C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Glycoprotein hormones alpha chain, also known as CGA, belongs to the glycoprotein hormones subunit alpha family. The subunit of CGA is a heterodimer consists of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. It has positive regulation of cell migration, cell proliferation and transcription from RNA polymerase II promoter and participates in the peptide hormone processing and signal transduction.

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