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Recombinant Human Clusterin/ApoJ Protein (Fc & His Tag)

Uniprot : P10909

Cat.No.:PKSH032261
Expression host: HEK293 Cells

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Description

Synonyms	Clusterin;Aging-Associated Gene 4 Protein;Apolipoprotein J;Apo-J;Complement Cytolysis Inhibitor;CLI;Complement-Associated Protein SP-40;Ku70-Binding Protein 1;NA1/NA2;Testosterone-Repressed Prostate Message 2;TRPM-2;CLU;APOJ;CLI;KUB1;AAG4;APO-J;CLU1;CLU2;NA1/NA2;SGP-2;SGP2;SP-40
Species	Human
Expression_host	HEK293 Cells
Sequence	Asp23-Glu449
Accession	P10909
Mol_Mass	78.0 kDa
AP_Mol_Mass	33-45&60-85 kDa
Tag	C-Fc-His

Properties

Purity	> 90 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed man
Reconstitution	Please refer to the printed manual for detailed information.

Background

Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis; heart; ovary; adrenal gland; brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death; tumor progression; and neurodegenerative disorders. In addition;Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer; organ regeneration; infection; Alzheimer disease; retinitis pigmentosa; myocardial infarction; renal tubular damage; autoimmunity and others.

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