Synonyms	Cystatin-A;Cystatin-AS;Stefin-A;CSTA;STF1;STFA
Species	Human
Expression_host	E.coli
Sequence	Ile2-Phe98
Accession	P01040
Mol_Mass	11.8 kDa
AP_Mol_Mass	14 kDa
Tag	N-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the print
Reconstitution	Please refer to the printed manual for detailed information.

Background

Human Cystatin A (CSTA) is a member of family 1 of the cystatin superfamily; which is characterized by lacking of disulphide bonds an carbohydrates. Cystatin A is an intracellular inhibitor regulating the activities of cysteine proteases of the papain family such as Cathepsins B; H and L. Cystatin A is also implicated in a number of disease states. Due to altered proteolytic state in cancer progression; Cystatin A may play a role in the proteolytic pathways.

Citations

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