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Recombinant Human Erythropoietin R/EPOR Protein (His Tag)

Uniprot : P19235

Cat.No.:PKSH033685
Expression host: HEK293 Cells

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Description

Synonyms	EpoR;EPO-R;Erythropoietin R;erythropoietin receptor;MGC138358;Platelet Receptor EPO-R
Species	Human
Expression_host	HEK293 Cells
Sequence	Ala25-Pro250
Accession	P19235
Mol_Mass	25.9 kDa
AP_Mol_Mass	28-38 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Trehalose, 3% Glycine, 0.05% Tween 80, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific b
Reconstitution	Please refer to the printed manual for detailed information.

Background

Erythropoietin (Epo); a glycoprotein produced primarily by the kidney; is the principal factor that regulates erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells. The biological effects of Epo are mediated by the erythropoietin receptor (Epo R). The presence of a soluble form of the Epo R has also been detected on human sera. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

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