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Recombinant Human Galectin 9/LGALS9 Protein (His Tag)

Uniprot : Q3B8N1

Cat.No.:PKSH032470
Expression host: HEK293 Cells

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Description

Synonyms	Galectin-9;Gal-9;Ecalectin;Tumor Antigen HOM-HD-21;LGALS9
Species	Human
Expression_host	HEK293 Cells
Sequence	Met 1-Thr323
Accession	Q3B8N1-2
Application	Functional ELISA
Mol_Mass	36.7 kDa
AP_Mol_Mass	49 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 50mM MOPS, 150mM NaCl, 1mM DTT, 1mM EDTA, 5% Trehalose, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific bu
Reconstitution	Please refer to the printed manual for detailed information.

Background

Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.

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