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Recombinant Human Gastric Lipase/LIPF Protein (Human Cells, His Tag)

Uniprot : P07098

Cat.No.:PKSH032480
Expression host: HEK293 Cells

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Description

Synonyms	HGL;HLAL;Gastric Triacylglycerol Lipase;GL;Gastric Lipase;LIPF
Species	Human
Expression_host	HEK293 Cells
Sequence	Leu20-Lys398
Accession	AAI12273.1
Mol_Mass	44.2 kDa
AP_Mol_Mass	50 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 100mM glycine, 10% Glycerol, pH 7.3.
Reconstitution	Not Applicable

Background

Gastric Triacylglycerol Lipase (LIPF) belongs to the AB hydrolase superfamily. LIPF is an important lipase during the digestion of dietary lipids in cystic fibrosis. LIPF is involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. LIPF is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. LIPF acts distinct roles in neutral lipid metabolism.

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