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Cat.No.:PKSH031865
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Synonyms | CD121b;CDw121b;IL-1R-2;IL-1RT-2;IL-1RT2;IL1R2c;IL1RB;Interleukin-1 receptor type 2;IL-1R-2;CD121 antigen-like family member B;CDw121b;IL-1 type II receptor;Interleukin-1 receptor beta;IL-1R-beta;Interleukin-1 receptor type I |
Species | Human |
Expression_host | HEK293 Cells |
Sequence | Met 1-Glu 343 |
Accession | NP_004624.1 |
Mol_Mass | 39.3 kDa |
AP_Mol_Mass | 50-55 kDa |
Tag | C-His |
Bio_Activity | 1. Measured by its ability to inhibit IL1β-dependent proliferation in D10.G4. 1 mouse helper T cells. The ED50 for this effect is typically 5. 5 μg/mL in the presence of 40 pg/mL of rhIL1β. 2. Measured by its ability to inhibit Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 500pg/mL IL1b. The EC50 for this effect is typically 20-80ng/mL. |
Purity | > 98 % as determined by reducing SDS-PAGE. |
Endotoxin level | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from sterile PBS, pH 7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |