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Recombinant Human Kallikrein 4/KLK4 Protein (His Tag)

Uniprot : Q9Y5K2

Cat.No.:PKSH032667
Expression host: HEK293 Cells

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Description

Synonyms	Kallikrein-4;Enamel Matrix Serine Proteinase 1;Kallikrein-Like Protein 1;KLK-L1;Prostase;Serine Protease 17;KLK4;EMSP1;PRSS17;PSTS;AI2A1;ARM1;EMSP;kallikrein;KLK-L1
Species	Human
Expression_host	HEK293 Cells
Sequence	Ser27-Ser254(His197Gln)
Accession	Q9Y5K2
Mol_Mass	25.4 kDa
AP_Mol_Mass	25-32 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the print
Reconstitution	Please refer to the printed manual for detailed information.

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

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