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Recombinant Human KLK-8/Kallikrein-8 Protein (His Tag)

Uniprot : O60259

Cat.No.:PKSH032669
Expression host: HEK293 Cells

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Description

Synonyms	Kallikrein-8;hK8;Neuropsin;NP;Ovasin;Serine Protease 19;Serine Protease TADG-14;Tumor-Associated Differentially Expressed Gene 14 Protein;KLK8;NRPN;PRSS19;TADG14
Species	Human
Expression_host	HEK293 Cells
Sequence	Gln29-GLy260
Accession	AAH40887.1
Mol_Mass	26.0 kDa
AP_Mol_Mass	35 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution	Not Applicable

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

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