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Recombinant Human Natriuretic Peptides B/NPPB Protein (His Tag)

Uniprot : P16860

Cat.No.:PKSH033585
Expression host: E.coli

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Description

Synonyms	Natriuretic Peptides B;Gamma-Brain Natriuretic Peptide;NPPB
Species	Human
Expression_host	E.coli
Sequence	His27-His134
Accession	P16860
Mol_Mass	14.2 kDa
AP_Mol_Mass	16 kDa
Tag	N-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, 1mM DTT, 20% Glycerol, pH 7.4.
Reconstitution	Not Applicable

Background

Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions; such as diuresis; natriuresis; vasorelaxation; which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water; improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.

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