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Recombinant Human Parvulin-14/PIN4 Protein (His Tag)

Uniprot : Q9Y237
  • Cat.No.:PKSH032859

  • Expression host: E.coli

To Purchase PKSH032859

Size:
  • 10μg
  • 50μg
Price: $263
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Description

Synonyms Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4;Parvulin-14;Parvulin-17;Peptidyl-prolyl cis-trans isomerase Pin4;Peptidyl-prolyl cis/trans isomerase EPVH;Rotamase Pin4;PIN4;
Species Human
Expression_host E.coli
Sequence Met 1-Lys156
Accession Q9Y237-2
Mol_Mass 18.8 kDa
AP_Mol_Mass 21 kDa
Tag N-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.5.
Reconstitution Not Applicable

Background

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stranded DNA.

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