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Recombinant Human Peroxiredoxin-4/PRDX4 Protein (His Tag)

Uniprot : Q13162
  • Cat.No.:PKSH032884

  • Expression host: E.coli

To Purchase PKSH032884

Size:
  • 10μg
  • 50μg
Price: $223
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Description

Synonyms Peroxiredoxin-4;Antioxidant Enzyme AOE372;AOE37-2;Peroxiredoxin IV;Prx-IV;Thioredoxin Peroxidase AO372;Thioredoxin-Dependent Peroxide Reductase A0372;PRDX4
Species Human
Expression_host E.coli
Sequence Trp38-Asn271
Accession Q13162
Mol_Mass 28.9 kDa
AP_Mol_Mass 30 kDa
Tag N-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution Not Applicable

Background

Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.

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