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Recombinant Human PPM1G/PP2C-gamma Protein (aa 317-546, His Tag)

Uniprot : O15355

Cat.No.:PKSH031182
Expression host: E.coli

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100μg

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Description

Synonyms	Protein Phosphatase 1G;Protein Phosphatase 1C;Protein Phosphatase 2C Isoform Gamma;PP2C-Gamma;Protein Phosphatase Magnesium-Dependent 1 Gamma;PPM1G;PP2CG;PP2CGAMMA
Species	Human
Expression_host	E.coli
Sequence	Met 317-Asp 546
Accession	O15355
Mol_Mass	26.6 kDa
AP_Mol_Mass	30 kDa
Tag	N-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	Please contact us for more information.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from sterile 50mM Tris, 1mM DTT, 20% glycerol, pH 7.5 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Protein phosphatase 1G; also known as Protein phosphatase 1C; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma; PP2C-gamma; PPM1G and PPM1C; is a cytoplasm protein which belongs to thePP2C family. PPM1G / PP2C-gamma is widely expressed. It is most abundant in testis; skeletal muscle; and heart. Alternatively spliced transcript variants encoding the same protein have been described. PP2C family members are known to be negative regulators of cell stress response pathways. PPM1G / PP2C-gamma is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors; which is important for the formation of functional spliceosome. PPM1G / PP2C-gamma also plays a role in regulating cell cycle progression.

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