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Recombinant Human PPM1G/PP2C-gamma Protein (His Tag)

Uniprot : O15355

Cat.No.:PKSH032970
Expression host: E.coli

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Description

Synonyms	Protein Phosphatase 1G;Protein Phosphatase 1C;Protein Phosphatase 2C Isoform Gamma;PP2C-Gamma;Protein Phosphatase Magnesium-Dependent 1 Gamma;PPM1G;PP2CG;PP2CGAMMA
Species	Human
Expression_host	E.coli
Sequence	Met317-Asp546
Accession	O15355
Mol_Mass	26.2 kDa
AP_Mol_Mass	30 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 1mM DTT, 1mM EDTA, 2mM β-ME, 20% Glycerol, pH 7.5.
Reconstitution	Not Applicable

Background

Protein Phosphatase 1G (PP1MG) is a cytoplasmic protein that belongs to the PP2C family. PPM1G is widely expressed; it is abundant in testis; skeletal muscle; and heart. PPM1G is a negative regulator of cell stress response pathways. PPM1G is responsible for the dephosphorylation of Pre-mRNA splicing factors; an important factor for the formation of functional spliceosome. PPM1G also plays a role in regulating cell cycle progression.

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