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Recombinant Human Ribonuclease K6/RNASE6 Protein (His Tag)

Uniprot : Q93091

Cat.No.:PKSH033003
Expression host: HEK293 Cells

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Description

Synonyms	Ribonuclease K6;RNase K6;RNASE6;RNS6
Species	Human
Expression_host	HEK293 Cells
Sequence	Trp24-Leu150
Accession	Q93091
Mol_Mass	15.7 kDa
AP_Mol_Mass	18-25 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5.
Reconstitution	Not Applicable

Background

Ribonuclease K6 (RNASE6) is a secreted protein that belongs to the pancreatic ribonuclease family. Human RNASE6 is synthesized as a 150 amino acid precursor that contains a 23 amino acid signal sequence, and a 127 amino acid mature chain. RNASE6 is expressed in many tissues, with high expression levels in the lung, with lower expression levels in the heart, placenta, kidney, pancreas, liver, brain, and skeletal muscle. It is also detected in monocytes and neutrophils. RNASE6 may have a role in host defense.

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