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Recombinant Human Tryptase β-2/TPSB2 Protein (His Tag)

Uniprot : P20231

Cat.No.:PKSH033154
Expression host: HEK293 Cells

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Description

Synonyms	Tryptase Beta-2;Tryptase-2;Tryptase II;TPSB2;TPS2
Species	Human
Expression_host	HEK293 Cells
Sequence	Ala19-Pro275
Accession	AAH29356.1
Mol_Mass	29.6 kDa
AP_Mol_Mass	30-35 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution	Not Applicable

Background

Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.

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