Current Position:Home>>Protein Products>>Recombinant Proteins>> Recombinant Mouse BACE2/Beta secretase 2 Protein (His Tag)

Recombinant Mouse BACE2/Beta secretase 2 Protein (His Tag)

Uniprot : Q9JL18

Cat.No.:PKSM040382
Expression host: HEK293 Cells

Filter:

To Purchase PKSM040382

Size:

100μg
1mg

Price: $1368

Qty:

Welcome to order from local distributors.

FAQs for Recombinant Proteins

Have Questions?

Add to cart Bulk request

For research use only. Order now, ship in 3 days

Description

Synonyms	1110059C24Rik;AEPLC;AI850424;ALP56;ARP1;ASP21;BAE2;CDA13;CEAP1;DRAP
Species	Mouse
Expression_host	HEK293 Cells
Sequence	Met1-Pro462
Accession	Q9JL18
Mol_Mass	49.2 kDa
AP_Mol_Mass	55 kDa
Tag	C-His
Bio_Activity	Measured by its ability to cleave a fluorogenic peptide substrate Mca-KPLGL-Dpa-AR-NH2. The specific activity is > 50 pmoles/min/μg.

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

BACE2, also known as beta secretase 2, belongs to the peptidase A1 family. It is a protease known to be an important enzyme involved in the cellular pathways. BACE2 has been shown to interact with GGA1 and GGA2. It is the major β-secretase in vivo. BACE2 is located on chromosome 21 and may play a role in alzheimer's disease pathogenesis in down syndrome(DS). Overexpression of BACE2 by lentivirus markedly reduced amyloid β protein production in primary neurons. Despite an extra copy of the BACE2 gene in DS and the increase of its transcription, BACE2 protein levels are unchanged.

Related Products

Proteins

Citations

Reviews/Q&A

Show all
Reviews
Q&A

... Show All Show Less

*Product Name:
*Catalog Number:
*Name:
*Email:
*Message:
*Country:
*When will you use it?	Within 1 month In 2 to 3 month In 4 to 6 month 6 months later
*Captcha:	Click to load Captcha