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Recombinant Mouse Carboxylesterase 1D/SES1D Protein (His Tag)

Uniprot : Q8VCT4
  • Cat.No.:PKSM040975

  • Expression host: HEK293 Cells

To Purchase PKSM040975

Size:
  • 10μg
  • 50μg
Price: $178
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Description

Synonyms CES3;carboxylesterase 3;carboxylesterase 3 (brain);EC 3.1.1;EC 3.1.1.1;ES31FLJ21736;Esterase 31;Liver carboxylesterase 31 homolog
Species Mouse
Expression_host HEK293 Cells
Sequence Tyr19-Glu561
Accession Q8VCT4
Mol_Mass 62.4 kDa
AP_Mol_Mass 58-70 kDa
Tag C-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the print
Reconstitution Please refer to the printed manual for detailed information.

Background

Mouse Carboxylesterases 3 (CES3) is a member of five families of mammalian carboxylesterases that plays a role in catalyzing hydrolytic and transesterification reactions with xenobiotics, anticancer pro-drugs and narcotics, and detoxifying organophosphates and insecticides. Mammalian carboxylesterases are enzymes with broad substrate specificities ranging from small molecule esters to longchain fatty acid esters. It is shown that CESs has key roles in the metabolism of a wide variety of clinical drugs, illicit narcotics and chemical nerve agents. CES3 is broadly expressed in liver, colon and brain.

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