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Recombinant Mouse Carboxylesterase 1D/SES1D Protein (His Tag)

Uniprot : Q8VCT4

Cat.No.:PKSM040714
Expression host: HEK293 Cells

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50μg

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Description

Synonyms	CES3;carboxylesterase 3;carboxylesterase 3 (brain);EC 3.1.1;EC 3.1.1.1;ES31FLJ21736;Esterase 31;Liver carboxylesterase 31 homolog
Species	Mouse
Expression_host	HEK293 Cells
Sequence	Met1-Glu561
Accession	NP_444430.2
Mol_Mass	60.8 kDa
AP_Mol_Mass	53 kDa
Tag	C-His
Bio_Activity	Measured by its ability to hydrolyze p-nitrophenylacetate. The specific activity is > 11000 pmoles/min/μg.

Properties

Purity	> 90 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Mouse Carboxylesterases 3 (CES3) is a member of five families of mammalian carboxylesterases that plays a role in catalyzing hydrolytic and transesterification reactions with xenobiotics, anticancer pro-drugs and narcotics, and detoxifying organophosphates and insecticides. Mammalian carboxylesterases are enzymes with broad substrate specificities ranging from small molecule esters to longchain fatty acid esters. It is shown that CESs has key roles in the metabolism of a wide variety of clinical drugs, illicit narcotics and chemical nerve agents. CES3 is broadly expressed in liver, colon and brain.

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