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Recombinant Mouse DDR2 Kinase/CD167b Protein (His Tag)

Uniprot : Q03146

Cat.No.:PKSM041190
Expression host: HEK293 Cells

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Description

Synonyms	Discoidin domain-containing receptor 2;Discoidin domain receptor 2;CD167 antigen-like family member B;Neurotrophic tyrosine kinase;receptor-related 3;Receptor protein-tyrosine kinase TKT;Tyrosine-protein kinase TYRO10;CD167b;Ddr2;Ntrkr3;tyro10
Species	Mouse
Expression_host	HEK293 Cells
Sequence	Gln24-Arg399
Accession	Q62371
Mol_Mass	43.5 kDa
AP_Mol_Mass	60-75 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Discoidin domain receptor-2 (DDR2) is a cell surface tyrosine kinase receptor that can be activated by soluble collagen and has been implicated in diverse physiological functions including organism growth and wound repair. DDR2 binds to and is activated by collagen I, II, III, V, and X, with the notable exception of basement membrane collagen IV. DDR2 is expressed in connective tissues arising from embryonic mesoderm. DDR2 regulates cell proliferation, cell adhesion, migration, and extracellular matrix remodeling.

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