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Recombinant Mouse FCRL1 Protein (aa 17-219, His Tag)

Uniprot : Q8R4Y0

Cat.No.:PKSM041196
Expression host: HEK293 Cells

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Description

Synonyms	Fc receptor-like protein 1;FcR-like protein 1;FcRL1;BXMAS1-like protein 1;mBXMH1;Fc receptor homolog 1;FcRH1;moFcRH1;IFGP family protein 1;mIFGP1;CD307a;Bxmas1;Bxmh1;Bxmh1b;Fcrh1;Fcrh1l;Fcrh1s;Ifgp1 Protein
Species	Mouse
Expression_host	HEK293 Cells
Sequence	Ala17-Ser219
Accession	BAC30017.1
Mol_Mass	22.5 kDa
AP_Mol_Mass	40-60 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Mouse Fc receptor-like protein 1 (FCRL1) is a single-pass type I membrane protein. It is expressed in B-cells at the various stages of differentiation. Mouse FCRL1 consists of a 203 amino acid (aa) extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 103 aa cytoplasmic domain with two immunotyrosine activation motifs (ITAMs). FCRL1 is likely not a receptor for immunoglobulin. It may function as an activating coreceptor in B-cells and B-cells differentiation.

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