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Current Position:Home>>Protein Products>>Recombinant Proteins>> Recombinant Rat Semaphorin 4D/SEMA4D/CD100 Protein (Fc Tag)

Recombinant Rat Semaphorin 4D/SEMA4D/CD100 Protein (Fc Tag)

  • Cat.No.:PKSR030237

  • Expression host: HEK293 Cells
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  • 100μg
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Description

Synonyms SEMA4D
Species Rat
Expression_host HEK293 Cells
Sequence Met1-Met712
Accession NP_001164034.1
Mol_Mass 103.4 kDa
AP_Mol_Mass 118 kDa
Tag C-hFc

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.

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