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Cat.No.:PKSH031898
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Synonyms | Serine/Threonine-Protein Kinase Receptor R3;SKR3;Activin Receptor-Like Kinase 1;ALK-1;TGF-B Superfamily Receptor Type I;TSR-I;ACVRL1;ACVRLK1;ALK1;HHT;HHT2;ORW2;SKR3 |
Species | Human |
Expression_host | HEK293 Cells |
Sequence | Met 1-Gln 118 |
Accession | NP_000011.2 |
Mol_Mass | 12.3 kDa |
AP_Mol_Mass | 27 kDa |
Tag | C-His |
Bio_Activity | Measured by its ability to inhibit BMP9 induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953. The ED50 for this effect is typically 50-200 ng/mL in the presence of 2 ng/mL of recombiant human BMP9. |
Purity | > 92 % as determined by reducing SDS-PAGE. |
Endotoxin level | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from sterile PBS, pH 7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |