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Recombinant Human DCBLD2/ESDN Protein (aa 1-482, His Tag)

Uniprot : Q96PD2
  • Cat.No.:PKSH030592

  • Expression host: HEK293 Cells

To Purchase PKSH030592

Size:
  • 100μg
Price: $732
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Description

Synonyms Discoidin;CUB and LCCL domain-containing protein 2;DCBLD2;CUB;LCCL and coagulation factor V/VIII-homology domains protein 1;Endothelial and smooth muscle cell-derived neuropilin-like protein;DCBLD2;CLCP1;ESDN
Species Human
Expression_host HEK293 Cells
Sequence Met 1-Ala482
Accession NP_563615.3
Mol_Mass 52.6 kDa
AP_Mol_Mass 69-89 kDa
Tag C-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV(1)-related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor mediated signaling pathway, negative regulation of cell growth and so on.

Citations

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