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Recombinant Human GOLPH2/GOLM1 Protein (aa 40-401, His Tag)

Uniprot : Q8NBJ4

Cat.No.:PKSH030746
Expression host: HEK293 Cells

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Description

Synonyms	Golgi Membrane Protein 1;Golgi Membrane Protein GP73;Golgi Phosphoprotein 2;GOLM1;C9orf155;GOLPH2
Species	Human
Expression_host	HEK293 Cells
Sequence	Val 40-Leu 401
Accession	Q8NBJ4-1
Mol_Mass	42.7 kDa
Tag	C-His

Properties

Purity	> 90 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Golgi membrane protein 1; also known as Golgi membrane protein GP73; Golgi phosphoprotein 2 and GOLM1; is a protein which belongs to theGOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in colon; prostate; trachea and stomach. It is expressed at lower level in testis; muscle; lymphoid tissues; white blood cells and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at low level in normal liver. Expression significantly increases in virus (HBV; HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease; autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH); GOLM1 is strongly expressed in hepatocyte-derived syncitial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.

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