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Current Position:Home>>Protein Products>>Recombinant Proteins>> Recombinant Human Kallikrein 11/KLK11 Protein (His Tag)

Recombinant Human Kallikrein 11/KLK11 Protein (His Tag)

  • Cat.No.:PKSH033404

  • Expression host: HEK293 Cells
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Description

Synonyms Kallikrein-11;hK11;Hippostasin;Serine Protease 20;Trypsin-Like Protease;KLK11;PRSS20;TLSP
Species Human
Expression_host HEK293 Cells
Sequence Glu19-Asn250
Accession AAH22068
Mol_Mass 26.3 kDa
AP_Mol_Mass 38 kDa
Tag C-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl2, pH 8.0.
Reconstitution Not Applicable

Background

Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide;a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.

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