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Recombinant Human PACSIN1/Syndapin-1 Protein (His Tag)

Uniprot : Q9BY11

Cat.No.:PKSH032845
Expression host: HEK293 Cells

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Description

Synonyms	Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1;PACSIN1;KIAA1379
Species	Human
Expression_host	HEK293 Cells
Sequence	Met 1-Ile444
Accession	Q9BY11
Mol_Mass	52.0 kDa
AP_Mol_Mass	50-67 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution	Not Applicable

Background

Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1 (PACSIN1) belongs to the PACSIN family. PACSIN1 contains one FCH domain and one SH3 domain. PACSIN1 is highly expressed in the brain and at lower leves in the heart, pancreas, and liver. PACSIN1 may play a role in vesicle formation and transport. PACSIN1 has been shown to interact with DNM1, PACSIN3, Huntingtin, and PACSIN2. In addition, PACSIN1 is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).

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