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Recombinant Human Placental Lactogen/CSH1 Protein (His Tag)

Uniprot : P0DML2

Cat.No.:PKSH032900
Expression host: HEK293 Cells

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Description

Synonyms	Chorionic Somatomammotropin Hormone;Choriomammotropin;Lactogen;Placental Lactogen;PL;CSH1;CSH2;CS-1;CSA;CSMT;hCS-1;hCS-A
Species	Human
Expression_host	HEK293 Cells
Sequence	Val27-Phe217
Accession	P0DML2
Mol_Mass	23.4 kDa
AP_Mol_Mass	24 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the print
Reconstitution	Please refer to the printed manual for detailed information.

Background

Chorionic Somatomammotropin Hormone (CSH1) belongs to the Somatotropin/Prolactin family. It is located at the growth hormone locus on chromosome 17. It is produced by cells in the syncytiotrophoblast layer of the placenta only during pregnancy. Although CSH1 does not interact with GHR but only activates PRLR through zinc-induced dimerization. It is expressed mainly in the placenta and utilizes multiple transcription initiation sites. CSH1 plays an important role in stimulating lactation, growth control and metabolism.

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