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Recombinant Human Progonadoliberin-2/GNRH2 Protein (His Tag)

Uniprot : O43555

Cat.No.:PKSH032936
Expression host: HEK293 Cells

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Description

Synonyms	Progonadoliberin-2;Progonadoliberin II;Gonadoliberin-2;Gonadoliberin II;Gonadotropin-Releasing Hormone II;GnRH II;Luliberin II;Luteinizing Hormone-Releasing Hormone II;LH-RH II;GnRH-Associated Peptide 2;GnRH-Associated Peptide II;GNRH2
Species	Human
Expression_host	HEK293 Cells
Sequence	Gln24-Val120
Accession	O43555
Mol_Mass	11.6 kDa
AP_Mol_Mass	14-25 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Progonadoliberin-2, also known as Progonadoliberin II and GNRH2, belongs to the gonadotropin-releasing hormone family. GNRH2 is specially expressed in midbrain, at significantly higher levels outside the brain (up to 30-fold). GNRH2 can be cleaved into two chains, gonadoliberin-2 and GnRH-associated peptide 2. gonadoliberin-2 regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. The proproteins produce three transcript variants, but produce the same peptide hormone.

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