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Recombinant Human Ribonuclease A/RNASE1 Protein (His Tag)

Uniprot : P07998

Cat.No.:PKSH033004
Expression host: HEK293 Cells

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Description

Synonyms	Ribonuclease Pancreatic;HP-Rnase;RIB-1;RNase UpI-1;Ribonuclease 1;RNase 1;Ribonuclease A;RNase A;RNASE1;RIB1;RNS1
Species	Human
Expression_host	HEK293 Cells
Sequence	Lys29-Thr156
Accession	P07998
Mol_Mass	15.6 kDa
AP_Mol_Mass	17-33 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 10% Glycerol, pH 7.4.
Reconstitution	Not Applicable

Background

Ribonuclease Pancreatic is a secreted enzyme that belongs to the pancreatic ribonuclease family. RNASE1 is an endonuclease that cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. RNASE1 prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. RNASE1 acts on single stranded and double stranded RNA.

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