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Recombinant Human SERPINB1/PI2 Protein (Baculovirus, His Tag)

Uniprot : P30740
  • Cat.No.:PKSH030808

  • Expression host: Baculovirus-Insect Cells

To Purchase PKSH030808

Size:
  • 50μg
Price: $732
Qty:

Description

Synonyms Leukocyte elastase inhibitor;SERPINB1;Monocyte/neutrophil elastase inhibitor;M/NEI;Peptidase inhibitor 2;PI-2;PI2;EI;ELANH2;HEL-S-27;HEL57;LEI;MNEI;
Species Human
Expression_host Baculovirus-Insect Cells
Sequence Met 1-Pro 379
Accession P30740
Mol_Mass 44.0 kDa
AP_Mol_Mass 44 kDa
Tag C-His

Properties

Purity > 90 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0, 10% glycerol
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healthy subjects and are negatively correlated with serum LDL-C. serpinB1 as an endogenous protein that can potentially be harnessed to enhance functional beta cell mass in patients with diabetes.

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