Synonyms	Alpha-Soluble NSF Attachment Protein;SNAP-Alpha;N-Ethylmaleimide-Sensitive Factor Attachment Protein Alpha;NAPA;SNAPA
Species	Human
Expression_host	E.coli
Sequence	Met 1-Arg295
Accession	P54920
Mol_Mass	35.4 kDa
AP_Mol_Mass	35 kDa
Tag	N-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the print
Reconstitution	Please refer to the printed manual for detailed information.

Background

α-Soluble NSF Attachment Protein (SNAP-α) is a member of the SNAP (Soluble NSF Attachment Protein) family. SNAP-α interacts with PRKCABP and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. SNAP-α is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. SNAP-α is in charge of the binding of NSF and therefore the formation of a 20S fusion particle.

Citations

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