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S100A8 Polyclonal Antibody

Cat:E-AB-70341
Manual MSDS

Price: $ 410

Price: $ 260

Price: $ 160

Size:
200μL 120μL 60μL
Quantity:
  • Host: Rabbit
  • Reactivity: Mouse;Rat
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Mouse Immunized spleen,Rat spleen
Dilution

IHC 1:200-1:800

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein corresponding to Mouse S100A8
Abbre S100A8
Synonyms 60B8Ag;AI323541;B8Ag;BEE11;CAGA;Calgranulin-A;Calprotectin L1L subunit;Calprotectin;included;CFAG;CGLA;Chemotactic cytokine CP-10;CP-10;Cystic fibrosis antigen;L1Ag;Leukocyte L1 complex light chain;MA387;MIF;Migration inhibitory factor-related protein 8;MRP-8;Myeloid-related protein 8;Neutrophil cytosolic 7 kDa protein;NIF;p8;Pro-inflammatory S100 cytokine;Protein S100-A8;S100 calcium binding protein A8 (calgranulin A);S100 calcium binding protein A8;S100 calcium-binding protein A8;S100A8;S100A8/S100A9 complex;included;S10A8;Urinary stone protein band A
Swissprot
Cellular Localization Secreted. Cytoplasm. Cytoplasm>cytoskeleton. Cell membrane. Associates with tubulin filaments in activated monocytes. Targeted to the cell surface upon calcium influx. Released from blood leukocytes upon exposure to CSF2/GM-CSF, bacterial lipopolysaccharide (LPS) and during inflammatory processes. Serum levels are high in patients suffering from chronic inflammation.
Concentration 0.8 mg/mL
Buffer PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method Affinity purification
Research Areas Cancer; Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Ice bag
background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.