F7 Polyclonal Antibody

Uniprot : P08709
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14394

      Synonyms:coagulation factor VII (serum prothrombin conversion accelerator),Coagulation factor VII,Eptacog alfa,F7,FA7,Factor VII,Factor VII heavy chain,Factor VII light chain,FVII coagulation protein,OTTHUMP00000018733,OTTHUMP00000018734,Proconvertin,Serum prothrombin conversion accelerator,SPCA

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms coagulation factor VII (serum prothrombin conversion accelerator),Coagulation factor VII,Eptacog alfa,F7,FA7,Factor VII,Factor VII heavy chain,Factor VII light chain,FVII coagulation protein,OTTHUMP00000018733,OTTHUMP00000018734,Proconvertin,Serum prothrombin conversion accelerator,SPCA
      Swissprot P08709
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human F7
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:25-1:100
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted.
      Tissue specificity Plasma.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

      Images

      Western Blot analysis of NIH/3T3, 293T and Jurkat cell using F7 Polyclonal Antibody at dilution of 1:400

      Immunohistochemistry of paraffin-embedded Human lung cancer using F7 Polyclonal Antibody at dilution of 1:40

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using F7 Polyclonal Antibody at dilution of 1:40

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