HK2 Polyclonal Antibody

Uniprot : P52789
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    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14706

      Synonyms:DKFZp686M1669,Hexokinase 2,Hexokinase 2 muscle,Hexokinase type II,Hexokinase-2,HK 2,HK II,HK2,HKII,HxK 2,HxK2,HXK2,Muscle form hexokinase

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms DKFZp686M1669,Hexokinase 2,Hexokinase 2 muscle,Hexokinase type II,Hexokinase-2,HK 2,HK II,HK2,HKII,HxK 2,HxK2,HXK2,Muscle form hexokinase
      Swissprot P52789
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human HK2
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:1000-1:5000, IHC 1:100-1:300
      Concentration 0.6 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding.
      Tissue specificity Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

      Images

      Western Blot analysis of A431, K562, 231, hela and hepG2 cell using HK2 Polyclonal Antibody at dilution of 1:1200

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using HK2 Polyclonal Antibody at dilution of 1:60

      Immunohistochemistry of paraffin-embedded Human lung cancer using HK2 Polyclonal Antibody at dilution of 1:60

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